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Technical Information by Appication

Pharmaceutical Applications

Polyvinyl alcohol is listed on the specifications of pharmaceutical excipients and used not only in Japan, but in the US, Europe, and other countries as well.
Our GOHSENOL™ EG complies with the excipient specifications of JPE, USP, as well as EP.
■Specialty Grades:High Purity PVOH EG Series

Features
The refining process of GOHSENOL™ EG removes impurities to the utmost.
Our production facilities, manufacturing process, and quality system are managed in compliance with our self-imposed standards of GMP.
Applications
  • ・Granulation binder
  • ・Binding agent
  • ・Coating
  • ・Thickener (eye-drop)
  • ・Gel Patch (cataplasm)
  • ・Emulsifier
  • ・Drug delivery film Substrate

example

Physical Property data
Comparison with Representative Pharmaceutical Excipients
●Comparison of film properties
Properties Polyvinyl Alcohol
(PVA)*1
Hydroxypropyl
Cellulose
(HPC)
Hydroxypropyl
Methyl Cellulose
(HPMC)
Viscosity*2
(mPa・s)
4.9 49.0 11.1
Tensile strength
(MPa)
119.4 5.1 46.9
Linear expansion
(%)
188.4 103.4 102.7
Young modulus
(MPa)
672 419 2,251

*1. Polyvinyl Alcohol : GOHSENOL™ EG-05PW
*2. 4% aqueous solution

●Barrier property
Properties Permeation rate
of O2 gas*2
(cc/m2・day・atm)
Permeation rate
of water vapor*3
(g/m2・day・atm)
25℃ 60%RH 40℃ 75%RH 25℃ 60%RH 40℃ 75%RH
PVA*1 0.74 18 3 85
HPC 128 >200 95 470
HPMC 152 >200 186 740

*1. Grades : GOHSENOLTM EG-05PW   Film thickness : 100μm (made by method of Pool cast)
*2Measuring machine of permeation of the O2 gas : OXTRAN2/20
*3. The method of permeation of water vapor : Comply with JIS Z 0208

Inquiry about EG series (Pharmaceutical Excipient Grades)
Acetyl and Fine Chemicals Dept. Basic Products Segment
TEL: +81-3-6436-2813 / FAX: +81-3-6436-2820


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